نموذج لامتحان الفارما الــmcq القادم المقرر عقده يوم الاثنين بعد القادم

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نموذج لامتحان الفارما الــmcq القادم المقرر عقده يوم الاثنين بعد القادم

مُساهمة من طرف Optimistic Doctor في 09/03/11, 12:18 pm

السلام عليكم ورحمة الله وبركاته
****

نموذج لامتحان الفارما الــmcq القادم
المقرر عقده يوم الاثنين اللى بعد القادم
اليكم الاسئلة نقلا عن رسالة دكتور شريف المعيد بقسم الفارماكولوجى ..
ووفق الله الجميع ,,


Shock examination model December 2010


1-Which of the following adverse effects (side-effects) is NOT commonly seen with
cholinergic antagonists?

a) Blurred vision
b) Confusion
c) Miosis
d) Constipation
e) Urinary retention

2-Which one of the following drugs may produce the following pharmacological actions:
Bronchial
dilation, coronary dilation, glycogenolysis ,Bronchial dilation,
coronary dilation, conversion of glycogen to glucose, isolated decrease
diastolic blood pressure:

a-Adrenaline
b-Noradrenaline
c-Isoprenaline
d-Formotrol

4- Which of the following is broken down by MAO-B (monoamine oxidase) more than
the others?

a) Serotonin (5-HT)
b) Norepinepherine (NE)
c) Dopamine (DA)

5-Which
of the following receptor subtypes is responsible for adrenaline
mediated increase in cardiac chronotropy (rate) and inotropy
(contractility), increases AV-node conduction velocity, and increases
rennin
secretion in renal juxtaglomerular cells?

a) 1 (Gq/Gi/Go)
b) 2 (Gi/Go)
c) 1 (Gs)
d) 2 (Gs)
e) 3 (Gs)

6- What is pilocarpine most commonly used for?
a) For decreasing heart rate
b) To decrease blood pressure (vasodilation)
c) For urinary retention
d) Decreasing intraocular pressure
e) For erectile dysfunction





7-
Which of the following receptor subtypes is responsible for
noradrenaline mediated decrease insulin secretion from pancreatic
-cells, muscle?

a) 1 (Gq/Gi/Go)
b) 2 (Gi/Go)
c) 1 (Gs)
d) 2 (Gs)
e) 3 (Gs)

8-A drug used in prophylaxis of bronchial asthma and acts by inhibition of intracellular calcium influx is:
a-Zulitin
b-Zaferikast
c-Disodium cromogycate
d-Ipratropium bromide

9- Impaired accommodation occurs with:
a phenothiazine
b. topical pilocarpine
c. topical atropine
d. topical phenylephrine
e. topical cocaine


10- Which of the following adrenergic receptor activation mechanisms is involved with
tricyclic antidepressants and cocaine?

a) Direct binding to the receptor
b) Promoting release of norepinephrine
c) Inhibiting reuptake of norepinephrine
d) Inhibiting inactivation of norepinephrine

11- A drug that blocks alpha adrenergic and serotonin receptors and stimulates dopamine receptors is;
a-Ergotamine
b-Phenoxybenzamine
c-Bromocriptine
d-Ergotamine

12- Which of the following would NOT be used as a topical vasoconstrictor for a patient
with epistaxis (nasal pack soaked in drug)?

a) Phenylephrine
b) Epinepherine
c) Oymetazoline
d) Isoprenaline

13- Which of the following agonists would be used for asthma patients or to delay
premature labor?

a) 2-agonist
b) 1-agonist
c) 3-agonist
d) 2-agonist
e) 1-agonist


14- Which of the following is the 1 drug of choice (DOC) for retinal exams and
surgery, giving mydiasis (dilation of iris)?

a) Ephedrine
b) Epinepherine
c) Phenylephrine
d) Isoproterenol

15- Which of the following drugs irreversibly damages norepinephrine storage vesicles?
a) Tyramine
b) Guanethidine
c) Reserpine
d) Propranolol
e) Epinepherine

16-Which of the following is the most likely to occur with parenteral administration of a
2-agonist drug?

a) Hypotension
b) Hypertension
c) Vasodilation
e) Lipolysis

17- Which of the following is NOT a result of excessive cholinergic stimulation, as
would be seen with a nerve agent or organophosphate poisoning?


a) Diarrhea
b) Diaphoresis
c) Mydriasis
d) Nausea
e) Urinary urgency





18- What drug is a natural alkaloid found in Solanaceae plants (deadly nightshade)?
a) Bethanechol
b) Pilocarpine
c) Pirenzepine
d) Scopolamine
e) Atropine

19- Which of the following is NOT true of catecholamines?
a) Non-polar
b) Cannot cross the blood-brain barrier
c) Cannot be used as an oral drug
d) Have brief duration
e) MAO and COMT act rapidly

20-Which
of the following G-protein is associated with acetyl choline induced
smooth muscle contraction and glandular tissue stimulation,

a) Gs
b) Gi
c) Gq
d) Go

21- Which of the following G-protein is associated with acetyl choline induced depression of SA node.
a) Gs
b) Gi
c) Gq
d) Go

22-The drugs bethanechol and pilocarpine are:
a) Acetylcholine agonists
b) Acetylcholine antagonists
c) Muscarinic agonists
d) Muscarinic antagonists
e) Acetylcholinesterase inhibitors

23- What two clinical results of topical administration of atropine?
a) Mydriasis (iris dilation) and increased lacrimation
b) Cycloplegia (ciliary paralysis) and miosis (iris constriction)
c) Miosis and increased lacrimation
d) Mydriasis and cycloplegia
e) Xerophthalmia (dry eyes) and mydriasis

24- Which of the following is an adverse affect of atropine?
a) Increased salivation
b) Blurred vision
c) Bradycardia
d) Diaphoresis
e) Decreased intraocular pressure
25- Which of the following is NOT a major symptom of atropine toxicity?
a) Blurring of vision
b) Skin flushing
c) Psychic stimulation
d) Hyperpyrexia
e) Hyperhydrosis

26- Of the following mydriatics/cycloplegics, ____ last 7-10 days (longest) and ____ last
6 hours (shortest).

a) Atropine; Scopolamine
b) Scopolamine; Homatropine
c) Homatropine; Tropicamide
d) Tropicamide; Atropine
e) Atropine; Tropicamide

27- Which of the following reversible cholinesterase inhibitors is used for atropine
intoxication?

a) Neostigmine
b) Physostigmine
c) Endrophonium
d) Donepezil
e) Pyridostigmine

28-Which of the following reversible cholinesterase inhibitors is used for Alzheimer
disease?

a) Neostigmine
b) Physostigmine
c) Endrophonium
d) Donepezil
e) Pyridostigmine

29- A drug that stimulates histaminic and muscarinic receptors and blocks alpha adrenergic receptors is:
a-Ergotamine
b-Phenoxybenzamine
c-Bromocriptine
d-Ergotamine

30- Which of the following is NOT an irreversible cholinesterase inhibitor
(organophosphate AChE inhibitors)?

a) Tacrine
b) Echothiophate
c) Sarin, toban, soman
d) Malathion, parathion
e) Isoflurophate

31- By what mechanism do irreversible ACHE inhibitors permanently bind to the
esteratic site enzyme?

a) Hydroxylation
b) Hydrolysis
c) Phosphorylation
d) Peptide
e) Methylation

32- Which of the following is NOT an effect of autonomic ganglion blocking?
a) Anhidrosis and xerostomia
b) Mydriasis
c) Tachycardia
d) Hypertension
e) Cycloplegia

33-. The effects of topically applied anticholinesterase on the eye include:
a. conjunctival hyperaemia
b. raised intraocular pressure
c. ciliary muscle contraction
d. sphincter pupillae muscle relaxation
e. retraction of the upper lids

34- Impaired accommodation occurs with:
a phenothiazine
b. topical pilocarpine
c. topical atropine
d. topical phenylephrine
e. topical cocaine

35-Which statement is true about Guanethidine:
A. Acts primarily at?/on? the CNS
B. Produces anti-hypertensive effect primarily by presynaptically inhibiting release of noradrenaline
C. Highly lipid soluble –
D. Mental depression is a troublesome side effect
E. Orthostatic hypotension is not a prominent side effect
[/b]


36- Labetalol:
A. Alpha agonist & beta agonist
B. Alpha agonist & beta antagonist
C. Alpha antagonist & beta antagonist





37-Which statement is true about Phentolamine:
A. Is a selective alpha-1 antagonist
B. Binds covalently to the alpha receptor
C. Causes bradycardia
D. Is a selective alpha-2 antagonist
E. Increases cardiac output



38- Which statement is true about Clonidine:
Which statement is true about
A. Causes hypertension and tachycardia after long term oral
B. Causes bradycardia
C.
A single dose given orally is significantly less effective then an
intravenous dose in the treatment of emergency hypertension
D. Counteracts the hypertensive response in pheochromocytoma



39- A drug that blocks histamine , serotonin and muscarinic receptors is
a-Phenoxybenzamine
b-Mestherid
c-Cyproheptide
d-Pizotifen

40- The drugs bethanechol and pilocarpine are:
a) Acetylcholine agonists
b) Acetylcholine antagonists
c) Muscarinic agonists
d) Muscarinic antagonists
e) Acetylcholinesterase inhibitors

41-Which is the second messenger responsible for norepinephrine mediated vascular smooth muscle contraction:
a-Adenyl cyclase stimulation.
B-Phospholipase c activation
c-Phospholipase A2
d-Increase sodium entry

42- Which of the following reversible cholinesterase inhibitors is used for Alzheimer
disease?

a) Neostigmine
b) Physostigmine
c) Endrophonium
d) Donepezil
e) Pyridostigmine



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Optimistic Doctor
 
 

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رد: نموذج لامتحان الفارما الــmcq القادم المقرر عقده يوم الاثنين بعد القادم

مُساهمة من طرف no way في 10/03/11, 01:05 pm


شكرا جزيلا

جزاكم الله خيرا


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no way
 
 

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تاريخ التسجيل : 11/10/2008

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رد: نموذج لامتحان الفارما الــmcq القادم المقرر عقده يوم الاثنين بعد القادم

مُساهمة من طرف ريتاج في 10/03/11, 05:34 pm

جزاكم الله كل خير ونفع بكم
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